Archived | Autism Speaks: High Risk, High Impact Projects (Winter 2008) | Circa 2008 #NotAnAutisticAlly

Doug Wallace, Ph.D., UC IrvineRichard Haas, M.D., UC San DiegoBeatrice Golomb, M.D., Ph.D., UC San Diego$690,460 for 1 year Mitochondrial Etiology of Autism The investigators propose to test the hypothesis that defects in mitochondrial function may be an important factor in ASD pathophysiology. Physiological and biochemical evidence of mitochondrial dysfunction will be directly assessed by …

Archived | Autism Speaks: 2008 Fellowship Grants | Circa 2008 #NotAnAutisticAlly

Christin Collins, Ph.D.Children's Hospital Boston$102,000 for 2 years Gene Expression Profiling of Autism Spectrum Disorders Autism Spectrum Disorders (ASDs) are likely caused by interactions between genetic and environmental factors which result in changes in neural development and activity. These changes might be associated with differences in the levels of expression of multiple different genes in …

Archived | Autism Speaks: International Epidemiology Grant Summaries (Winter 2008) | Circa 2008 #NotAnAutisticAlly

Shuaib Kauchali, PhDUniversity of KwaZulu-Natal, Nelson R Mandela School of Medicine, South Africa; and Columbia University, Mailman School of Public Health, New York, NYTotal: $120,000 for 2 years KwaZulu-Natal (KZN) Autism Study Little is known about how frequently Autism Spectrum Disorder (ASD) occurs in children in developing countries. The primary aim of the KZN Autism Study …

Archived | Autism Speaks: 2008 Basic and Clinical Awards (Summer) | Circa 2008 #NotAnAutisticAlly

2008 Basic and Clinical Awards (Summer) Glenys Dixon, B PsychTelethon Institute for Child Health Research$128,045 for 2 years International trends in diagnoses and incidence of autism spectrum disorders Although there have been numerous studies investigating the increased prevalence or "epidemic" or autism spectrum disorders (ASDs), it is still not clear whether this relates to a …

Archived | Autism Speaks: 2008 Basic and Clinical Awards (Winter) | Circa 2008 #NotAnAutisticAlly

Theo Palmer, Ph.D.Stanford UniversityTotal: $382,500 for 3 years Maternal Infection and Autism: Impact of Placental Sufficiency and Maternal Inflammatory Responses on Fetal Brain Development Maternal infections during pregnancy have been linked to an increased risk of autism and other neurological disorders in the child. Dr. Palmer's laboratory has found that giving a mild infection to …

Archived | Autism Speaks: Environmental Factors in Autism Initiative | Circa 2008 #NotAnAutisticAlly

Environmental Factors Initiative  Although we know that genetics is an important factor, genetics alone may not account for all cases of autism. The increase in the reported number of autism cases has generated extreme concern over the potential involvement of toxins as well as infectious agents in our environment.  The role of environmental factors in …

Archived | Autism Speaks: 2008 Environmental Factors and Autism Grants | Circa 2008 #NotAnAutisticAlly

David Baskin, M.D.The Methodist Hospital, Houston$60,000 for one yearDifferential Effects of Thimerosal on Cell Division and Apoptosis in Normal vs Autism Spectrum Disorder Cell LinesThis study will investigate the effects of a dose-dependent exposure of thimerosal on cell proliferation. First, thimerosal will be exposed to immortalized lymphocyte cell lines from autistic and non-autistic individuals as …